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IN VIVO ASSESSMENT OF SKIN IMPEDANCE RECOVERY AFTER LOW-VOLTAGE PULSES ELECTROPORATION

Pasquale Arpaia, Fabrizio Clemente, Carlo Manna
  • Abstract:
    The aim of this work is to measure the skin impedance recovery after electroporation by using low-voltage pulse protocol on human subject. Before and after electroporation, based on square wave pulses of 20-50 V, 5 μs, for 15-20 minutes, Electrical Impedance Spectroscopy (EIS) measurements has been performed, in the frequency range 0.5-10 kHz. Preliminary experimental results show a significant decrease in skin impedance amplitude after treatment. This result turns out to be useful in a measurement procedure aimed at determining the amount of drug actually transferred in electroporation-based therapy.
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  • DOI:
    _unreg_tc4-2008.179

Event details:

  • IMEKO TC:
    TC4
  • Event name:
    Exploring New Frontiers of Instrumentation and Methods for Electrical and Electronic Measurements
  • Title:
    XVIth IMEKO TC4 International Symposium on Electrical Measurements and Instrumentation (together with 13th IMEKO TC4 Workshop on ADC Modelling and Testing)
  • Place:
    Florence, ITALY
  • Time:
    22 September 2008 - 24 September 2008