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Development of metabolomics for Alternaria toxins as a model for risk assessment of mycotoxins
Gotthardt, M., Kanawati, B., Schmitt-Kopplin, P., Rychlik, M.
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Abstract:A stable isotope dilution LC-MS/MS method was developed for the Alternaria toxins alternariol (AOH), alternariol monomethylether (AME) and tenuazonic acid (TeA) in herbs. Tentoxin (TEN) was quantified using matrix calibration. Solid phase extraction was applied for sample purification. Limits of detection (LOD) and quantification (LOQ), recoveries and intra- and interday precisions were determined for a comprehensive validation. The method was used to evaluate the mycotoxin contamination in various herbs and infusions.
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Keywords:Alternaria toxins, SIVA, LC-MS/MS
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DOI:_unreg_tc23-2017.091
Event details:
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IMEKO TC:TC23
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Event name:3rd IMEKOFOODS Conference
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Title:
Metrology Promoting Standardization and Harmonization in Food and Nutrition
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Place:Thessaloniki, GREECE
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Time:01 October 2017 - 04 October 2017